Description

(R)-Benzyl 2-Isopropyl-3-Oxo-3,4-Dihydropyrazine-1(2H)-Carboxylate is a high-purity chiral intermediate of significant importance in advanced organic synthesis. This compound matters for its role as a key building block in the development of complex, biologically active molecules, particularly within the pharmaceutical sector. It is primarily needed by research and development teams in pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active pharmaceutical ingredients (APIs) and other specialty compounds.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel Active Pharmaceutical Ingredients (APIs), particularly in therapeutic areas requiring stereochemical precision.
• Agrochemical Synthesis: Used as a building block in the creation of advanced, enantiomerically pure pesticides and herbicides.
• Fine Chemical Production: Serves as a precursor in the multi-step synthesis of complex specialty chemicals and flavors/fragrances.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development in asymmetric synthesis and heterocyclic chemistry.
• Peptidomimetic Research: The dihydropyrazinone core is valuable for constructing peptidomimetic scaffolds in drug discovery programs.
• Catalyst & Ligand Development: Can be utilized as a precursor or framework for developing novel chiral catalysts and ligands.

Basic Information

Product Name	(R)-Benzyl 2-Isopropyl-3-Oxo-3,4-Dihydropyrazine-1(2H)-Carboxylate
CAS No.	1456693-01-8
Molecular Formula	C15H18N2O3
Molecular Weight	274.32 g/mol
Synonyms	(R)-Benzyl 2-(propan-2-yl)-3-oxo-3,4-dihydropyrazine-1(2H)-carboxylate; (R)-1-(Benzyloxycarbonyl)-2-isopropyl-3-oxo-1,2,3,4-tetrahydropyrazine; (R)-Cbz-2-Isopropyl-3-oxo-1,2,3,4-tetrahydropyrazine; (R)-1-N-Cbz-2-isopropyl-3-oxopiperazine; Benzyl (R)-2-isopropyl-3-oxo-3,4-dihydro-2H-pyrazine-1-carboxylate; (R)-2-Isopropyl-3-oxo-1,2,3,4-tetrahydropyrazine-1-carboxylic acid benzyl ester
EINECS	Contact for details

Quality Control

Our (R)-Benzyl 2-Isopropyl-3-Oxo-3,4-Dihydropyrazine-1(2H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting R&D and cGMP standards for advanced intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.