Description

3-Bromo-5-Iodopyrazin-2-Amine is a high-purity, multi-halogenated pyrazine derivative serving as a critical building block in advanced organic synthesis. Its unique halogen pattern makes it an exceptionally valuable intermediate for constructing complex heterocyclic scaffolds with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Research: Used to develop new active ingredients for crop protection products, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a building block for creating functional organic materials, such as ligands for catalysts or components in organic electronics.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Cross-Coupling Reactions: The bromine and iodine substituents provide orthogonal reactivity for sequential metal-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Heterocyclic Chemistry: A versatile substrate for further functionalization and annulation reactions to create diverse nitrogen-containing heterocycles.

Basic Information

Product Name	3-Bromo-5-Iodopyrazin-2-Amine
CAS No.	1449112-32-6
Molecular Formula	C4H3BrIN3
Molecular Weight	299.90 g/mol
Synonyms	2-Amino-3-bromo-5-iodopyrazine; 5-Iodo-3-bromopyrazin-2-amine; 3-Bromo-5-iodo-2-pyrazinamine; 2-Pyrazinamine, 3-bromo-5-iodo-; 1449112-32-6; 3-Bromo-5-iodopyrazin-2-ylamine
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Iodopyrazin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports your research and development needs with reliable, high-purity materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere or in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.