Description

n-(Piperidin-4-Yl)Pyrazin-2-Amine Dihydrochloride is a high-purity chemical building block and intermediate of significant interest in advanced organic synthesis. Its core value lies in its functionalized piperidine-pyrazine scaffold, which is a privileged structure for modulating biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on discovering new active ingredients for therapeutic and crop protection applications.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, especially in kinase inhibitor and central nervous system (CNS) targeted research.
• Agrochemical Research: Used as a key building block for developing new active ingredients in crop protection and pest management solutions.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and tool compounds for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring complex, nitrogen-containing heterocycles.
• Academic & Institutional Research: Utilized in university and research institute laboratories for methodological development and exploring new chemical spaces.

Basic Information

Product Name	n-(Piperidin-4-Yl)Pyrazin-2-Amine Dihydrochloride
CAS No.	1448854-99-6
Molecular Formula	C9H15Cl2N5
Molecular Weight	264.16 g/mol
Synonyms	2-Pyrazinamine, N-4-piperidinyl-, dihydrochloride; 4-(Pyrazin-2-ylamino)piperidine dihydrochloride; N-(Piperidin-4-yl)pyrazin-2-amine dihydrochloride; 1-(Piperidin-4-yl)pyrazin-2-amine dihydrochloride; 2-((Piperidin-4-yl)amino)pyrazine dihydrochloride; 1448854-99-6; 4-(2-Pyrazinylamino)-1-piperidine dihydrochloride
EINECS	Contact for details

Quality Control

Every batch of n-(Piperidin-4-Yl)Pyrazin-2-Amine Dihydrochloride is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We provide full traceability and guarantee batch-to-batch consistency to support your critical R&D and scale-up activities. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.