Description

3,5-Dichloro-2-Cyclopropylpyrazine is a high-purity, functionalized pyrazine derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both halogen and cyclopropyl substituents, makes it a versatile intermediate for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Synthesis: Used to develop new generations of herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a scaffold for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Building block for organic electronic materials, such as components for organic light-emitting diodes (OLEDs) or semiconductors.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Item	Details
Product Name	3,5-Dichloro-2-Cyclopropylpyrazine
CAS No.	1448241-45-9
Molecular Formula	C7H6Cl2N2
Molecular Weight	189.04 g/mol
Synonyms	2-Cyclopropyl-3,5-dichloropyrazine; 3,5-Dichloro-2-cyclopropylpyrazine; Pyrazine, 3,5-dichloro-2-cyclopropyl-; 1448241-45-9; 2-Cyclopropyl-3,5-dichloro-1,4-diazine
EINECS	Contact for details

Quality Control

Our 3,5-Dichloro-2-Cyclopropylpyrazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids and organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.