Description

tert-Butyl 4-(4-Formyl-3-Hydroxyphenyl)Piperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a unique piperazine scaffold with both formyl and phenolic hydroxyl functional groups. This compound is critical for medicinal chemistry research and development, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for the discovery of new active pharmaceutical ingredients (APIs).
• Chemical Synthesis: The reactive aldehyde and hydroxyl groups make it a versatile precursor for further functionalization, including condensation and coupling reactions.
• Bioconjugation & Probe Development: Potential use in creating chemical probes or conjugates for biochemical and diagnostic applications.
• Academic & Industrial R&D: Essential for research institutions and CROs (Contract Research Organizations) developing novel heterocyclic compounds.

Basic Information

Product Name	tert-Butyl 4-(4-Formyl-3-Hydroxyphenyl)Piperazine-1-Carboxylate
CAS No.	1446332-69-9
Molecular Formula	C16H22N2O4
Molecular Weight	306.36 g/mol
Synonyms	Boc-4-(4-Formyl-3-hydroxyphenyl)piperazine; 1-Boc-4-(4-Formyl-3-hydroxyphenyl)piperazine; 1-(tert-Butoxycarbonyl)-4-(4-formyl-3-hydroxyphenyl)piperazine; tert-Butyl 4-(4-formyl-3-hydroxyphenyl)piperazine-1-carboxylate; 4-(4-Formyl-3-hydroxyphenyl)piperazine-1-carboxylic acid tert-butyl ester; 1446332-69-9; 4-Formyl-3-hydroxy-phenyl-piperazine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(4-Formyl-3-Hydroxyphenyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles suitable for pharmaceutical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, consider storing under an inert atmosphere (e.g., nitrogen or argon) in a desiccated environment. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.