Description

Pyrazine, 5-Chloro-2,3-Bis(3,5-Dimethylphenyl)- is a high-purity, advanced organic intermediate characterized by its substituted pyrazine core flanked by two 3,5-dimethylphenyl groups. This compound matters for its role as a critical building block in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. Industrial and research chemists need this specific chlorinated pyrazine derivative for developing active ingredients and novel materials where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders or possessing kinase inhibitory activity.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated heterocyclic structure.
• Material Science Research: Serves as a monomer or functional unit in the development of organic semiconductors, liquid crystals, or metal-organic frameworks (MOFs) due to its rigid, aromatic structure.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce complex aryl-substituted pyrazine motifs into target molecules.
• Chemical Research & Development: Utilized in academic and industrial R&D labs for exploring new reaction pathways and creating libraries of novel heterocyclic compounds for screening.

Basic Information

Product Name	Pyrazine, 5-Chloro-2,3-Bis(3,5-Dimethylphenyl)-
CAS No.	1443732-36-2
Molecular Formula	C20H19ClN2
Molecular Weight	322.83 g/mol
Synonyms	5-Chloro-2,3-bis(3,5-dimethylphenyl)pyrazine; 2,3-Bis(3,5-dimethylphenyl)-5-chloropyrazine; 5-Chloro-2,3-di(3,5-xylyl)pyrazine; 1443732-36-2; Chloro-bis(dimethylphenyl)pyrazine; Aryl-substituted chloropyrazine
EINECS	Contact for details

Quality Control

Our Pyrazine, 5-Chloro-2,3-Bis(3,5-Dimethylphenyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.