Description

3,5-Dinitro-4-Piperazin-1-Ylbenzoic Acid Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its specific aromatic substitution pattern. This compound matters as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting specific receptor pathways. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, where precise chemical structure and reliable purity are paramount for successful outcomes.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly in medicinal chemistry programs.
• API Synthesis: Used in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs), where its nitro and piperazine groups serve as handles for further functionalization.
• Chemical Research: Serves as a valuable reagent in academic and industrial research for studying structure-activity relationships (SAR) and developing novel heterocyclic compounds.
• Preclinical Development: Employed in the production of compounds for pharmacological screening, toxicology studies, and early-stage drug development.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized fine chemicals for client projects.

Basic Information

Product Name	3,5-Dinitro-4-Piperazin-1-Ylbenzoic Acid Hydrochloride
CAS No.	1443424-56-3
Molecular Formula	C11H13N5O6 • HCl
Molecular Weight	359.71 g/mol
Synonyms	4-(Piperazin-1-yl)-3,5-dinitrobenzoic acid hydrochloride; Benzoic acid, 3,5-dinitro-4-(1-piperazinyl)-, hydrochloride; 3,5-Dinitro-4-(piperazin-1-yl)benzoic acid HCl; 3,5-Dinitro-4-piperazin-1-yl-benzoic acid hydrochloride; 1443424-56-3
EINECS	Contact for details

Quality Control

Our 3,5-Dinitro-4-Piperazin-1-Ylbenzoic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee full traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to protect from moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.