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4α,8β-Dihydroxy-3α-(2-Hydroxy-3-Acetoxy-2-Methylbutyryloxy)Eudesm-7(11)-En-12,8α-Olide CAS NO 1442989-33-4


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CAS No.:1442989-33-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4α,8β-Dihydroxy-3α-(2-Hydroxy-3-Acetoxy-2-Methylbutyryloxy)Eudesm-7(11)-En-12,8α-Olide is a high-purity, structurally complex sesquiterpene lactone derivative of significant interest in advanced organic synthesis and pharmaceutical research. Its intricate molecular architecture, featuring multiple chiral centers and functional groups, makes it a valuable advanced intermediate or reference standard for developing novel bioactive compounds. This compound is primarily sought by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of new therapeutic agents or natural product analogs.

Application

  • Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of potential new drug candidates, particularly in oncology and anti-inflammatory research.
  • Natural Product Chemistry: Used as a reference standard or starting material for the semi-synthesis of complex eudesmane-type sesquiterpenoids.
  • Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore the biological activity of modified sesquiterpene lactone scaffolds.
  • Biochemical Research: Investigated for its potential interactions with specific enzymes or cellular pathways due to its lactone functionality.
  • Fine Chemical Synthesis: Acts as a sophisticated precursor for creating specialty chemicals with high added value in the agrochemical or fragrance industries.
  • Academic Research: Utilized in universities and research institutes for methodological studies in complex molecule synthesis and stereochemistry.

Basic Information

Product Name 4α,8β-Dihydroxy-3α-(2-Hydroxy-3-Acetoxy-2-Methylbutyryloxy)Eudesm-7(11)-En-12,8α-Olide
CAS No. 1442989-33-4
Molecular Formula C22H32O9
Molecular Weight 440.49 g/mol
Synonyms 4α,8β-Dihydroxy-3α-(2-hydroxy-3-acetoxy-2-methylbutyryloxy)eudesm-7(11)-en-12,8α-olide; (3α,4α,8α,8β)-4,8-Dihydroxy-3-[(2-hydroxy-3-acetoxy-2-methyl-1-oxobutoxy)]eudesm-7(11)-en-12,8-olide; Eudesmane-12,8α-olide derivative; Sesquiterpene lactone acetate ester; 4,8-Dihydroxy-3-(2-hydroxy-3-acetoxy-2-methylbutanoyloxy)eudesm-7(11)-en-12,8α-olide
EINECS Contact for details

Quality Control

Our 4α,8β-Dihydroxy-3α-(2-Hydroxy-3-Acetoxy-2-Methylbutyryloxy)Eudesm-7(11)-En-12,8α-Olide is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and specific optical rotation measurement to ensure identity and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to cGMP principles in manufacturing and handling ensures a reliable supply of this high-value research chemical.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. The compound may be sensitive to prolonged exposure to moisture and elevated temperatures.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to reference spectrum
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Specific Optical Rotation Contact for details
Loss on Drying ≤ 2.0%
Residue on Ignition ≤ 0.5%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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