Description

S-n-Cbz-2-Hydroxymethylmorpholine is a high-purity, protected morpholine derivative designed for advanced pharmaceutical synthesis and fine chemical research. This compound serves as a critical chiral building block and intermediate, enabling the construction of complex molecules with precise stereochemistry. It is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Peptidomimetic Synthesis: Used in the construction of peptidomimetics and constrained peptide analogs due to its morpholine scaffold and hydroxymethyl functionality.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing novel chiral ligands and organocatalysts.
• Agrochemical Research: Employed as an intermediate in the development of advanced herbicides and fungicides with specific stereochemical requirements.
• Custom Chemical Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects requiring high stereochemical purity.
• Academic Research: A valuable tool in university and institutional labs for methodological studies in organic synthesis and medicinal chemistry.

Basic Information

Product Name	S-n-Cbz-2-Hydroxymethylmorpholine
CAS No.	1439373-46-2
Molecular Formula	C14H19NO4
Molecular Weight	265.31 g/mol
Synonyms	(S)-2-(((Benzyloxy)carbonyl)aminomethyl)morpholine; (S)-N-((Morpholin-2-yl)methyl)carbamic acid benzyl ester; (S)-2-(Cbz-aminomethyl)morpholine; (S)-N-Cbz-2-Aminomethylmorpholine; S-Cbz-2-Aminomethylmorpholine; (S)-2-((((Benzyloxy)carbonyl)amino)methyl)morpholine; Benzyl ((S)-morpholin-2-ylmethyl)carbamate
EINECS	Contact for details

Quality Control

Our S-n-Cbz-2-Hydroxymorpholine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.