Description

2-Fluoro-4-(2-Methyl-8-((3-(Methylsulfonyl)Benzyl)Amino)Imidazo[1,2-A]Pyrazin-3-Yl)Phenol is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel therapeutic agents. This compound is critical for research and development in medicinal chemistry, offering a sophisticated scaffold for targeting specific biological pathways. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of targeted kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Serves as a reference standard or probe in enzymatic assays and target validation studies.
• Fine Chemical Synthesis: Intermediate for the production of complex, fluorinated heterocyclic compounds with potential biological activity.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.

Basic Information

Product Name	2-Fluoro-4-(2-Methyl-8-((3-(Methylsulfonyl)Benzyl)Amino)Imidazo[1,2-A]Pyrazin-3-Yl)Phenol
CAS No.	1436383-95-7
Molecular Formula	C21H18FN5O3S
Molecular Weight	439.46 g/mol
Synonyms	2-Fluoro-4-[2-methyl-8-[[3-(methylsulfonyl)phenyl]methylamino]imidazo[1,2-a]pyrazin-3-yl]phenol; Phenol, 2-fluoro-4-[2-methyl-8-[[[3-(methylsulfonyl)phenyl]methyl]amino]imidazo[1,2-a]pyrazin-3-yl]-; 1436383-95-7; Imidazo[1,2-a]pyrazine derivative with fluorophenol and methylsulfonylbenzylamino substituents
EINECS	Contact for details

Quality Control

Our production of 2-Fluoro-4-(2-Methyl-8-((3-(Methylsulfonyl)Benzyl)Amino)Imidazo[1,2-A]Pyrazin-3-Yl)Phenol adheres to stringent quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We operate under a quality system designed to meet the standards required for cGMP and non-GMP pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.