Description

2-Bromo-5-(4-Methoxybenzyl)-5H-Pyrrolo[2,3-B]Pyrazine is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound is critical for research and development in the pharmaceutical sector, where it serves as a key intermediate for constructing novel active pharmaceutical ingredients (APIs). It is primarily utilized by medicinal chemists and process development scientists in pharmaceutical, agrochemical, and advanced materials research to introduce specific molecular complexity and functionality.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Development: Serves as a precursor in the creation of novel herbicides and fungicides with specific modes of action.
• Chemical Biology Probes: Employed in the development of molecular probes for studying biological pathways and target engagement.
• Organic Electronic Materials: Potential use as a precursor for constructing nitrogen-rich heterocyclic cores in organic semiconductors.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific advanced intermediates under cGMP conditions where required.

Basic Information

Product Name	2-Bromo-5-(4-Methoxybenzyl)-5H-Pyrrolo[2,3-B]Pyrazine
CAS No.	1434141-87-3
Molecular Formula	C14H12BrN3O
Molecular Weight	318.17 g/mol
Synonyms	2-Bromo-5-[(4-methoxyphenyl)methyl]-5H-pyrrolo[2,3-b]pyrazine; 5-[(4-Methoxyphenyl)methyl]-2-bromo-5H-pyrrolo[2,3-b]pyrazine; 2-Bromo-5-(4-methoxybenzyl)-5H-pyrrolo[2,3-b]pyrazine; Pyrrolo[2,3-b]pyrazine, 2-bromo-5-[(4-methoxyphenyl)methyl]-5H-; 1434141-87-3; 2-Bromo-5-(p-methoxybenzyl)-5H-pyrrolo[2,3-b]pyrazine
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-(4-Methoxybenzyl)-5H-Pyrrolo[2,3-B]Pyrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to relevant ISO standards, and we support development under ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.