Description

(1S,6R)-3-Methyl-3,8-Diazabicyclo[4.2.0]Octane is a high-purity, chiral bicyclic amine building block of significant interest in advanced organic synthesis. Its constrained, nitrogen-rich scaffold makes it a valuable intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is primarily sought after by medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where stereochemical control is critical.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of potential drug candidates, especially for central nervous system (CNS) and infectious disease targets.
• Ligand Precursor: Serves as a starting material for the development of novel chiral ligands used in asymmetric catalysis.
• Agrochemical Research: Used in the discovery and development of new, stereochemically-defined pesticides and herbicides.
• Chemical Biology Probes: Incorporated into molecular probes to study enzyme mechanisms and protein-ligand interactions due to its rigid structure.
• Advanced Material Synthesis: A building block for creating novel polymers or functional materials with specific chemical properties.
• Academic & Contract Research: Essential for research institutions and CROs (Contract Research Organizations) exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	(1S,6R)-3-Methyl-3,8-Diazabicyclo[4.2.0]Octane
CAS No.	1434127-03-3
Molecular Formula	C7H14N2
Molecular Weight	126.20 g/mol
Synonyms	(1S,6R)-3-Methyl-3,8-diazabicyclo[4.2.0]octane; 3-Methyl-3,8-diazabicyclo[4.2.0]octane, (1S,6R)-; (1S,6R)-3-Methyl-3,8-diazabicyclo[4.2.0]octane; Bicyclo[4.2.0]octane, 3-methyl-3,8-diaza-, (1S,6R)-; SCHEMBL21825027; AKOS040759991; F2198-6695; (1S,6R)-3-Methyl-3,8-diazabicyclo[4.2.0]octane hydrochloride (salts)
EINECS	Contact for details

Quality Control

Our (1S,6R)-3-Methyl-3,8-Diazabicyclo[4.2.0]Octane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including chiral purity verification by HPLC, to meet exacting customer specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.