Description

[1,2,4]Triazolo[1,5-A]Pyrazin-2-Yl-Carbamic Acid tert-Butyl Ester is a high-purity, heterocyclic organic compound featuring a fused triazolopyrazine core, serving as a critical advanced pharmaceutical intermediate (API intermediate) and key building block in modern synthetic chemistry. Its molecular architecture makes it indispensable for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex nitrogen-containing heterocycles. This compound is primarily utilized by pharmaceutical R&D laboratories, contract research and manufacturing organizations (CROs/CMOs), and academic research institutions focused on medicinal chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in high-throughput screening campaigns.
• API Development: Used in the process development and scale-up of Active Pharmaceutical Ingredients (APIs) that incorporate the triazolopyrazine pharmacophore.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Agrochemical Research: Potential intermediate in the development of new herbicides or fungicides that utilize nitrogen-rich heterocyclic systems.
• Academic & Institutional Research: A valuable reagent for methodological studies in organic synthesis, including novel cross-coupling and cyclization reactions.

Basic Information

Item	Detail
Product Name	[1,2,4]Triazolo[1,5-A]Pyrazin-2-Yl-Carbamic Acid tert-Butyl Ester
CAS No.	1434053-26-5
Molecular Formula	C10H13N5O2
Molecular Weight	235.25 g/mol
Synonyms	tert-Butyl [1,2,4]triazolo[1,5-a]pyrazin-2-ylcarbamate; 2-(((tert-Butoxy)carbonyl)amino)-[1,2,4]triazolo[1,5-a]pyrazine; BOC-Protected 2-Amino[1,2,4]triazolo[1,5-a]pyrazine; N-Boc-2-amino[1,2,4]triazolo[1,5-a]pyrazine; [1,2,4]Triazolo[1,5-a]pyrazin-2-amine, N-[(1,1-dimethylethoxy)carbonyl]-; 1434053-26-5; tert-Butyl (1,2,4-triazolo[1,5-a]pyrazin-2-yl)carbamate
EINECS	Contact for details

Quality Control

Our [1,2,4]Triazolo[1,5-A]Pyrazin-2-Yl-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All batches are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Our quality protocols are designed to meet the stringent requirements of pharmaceutical intermediate supply, supporting our clients' regulatory submissions and process development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.