Description

2-(Bromomethyl)-5-Chloropyrazine is a versatile halogenated pyrazine derivative, a crucial building block in advanced organic synthesis. Its molecular structure, featuring both bromomethyl and chloro substituents on the pyrazine ring, makes it a highly reactive intermediate for constructing complex heterocyclic systems. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides requiring specific pyrazine-based scaffolds.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and material science.
• Functional Material Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers.
• Custom Chemical Synthesis: Provides a reactive handle for medicinal chemistry and process R&D for introducing functional groups via nucleophilic substitution.

Basic Information

Product Name	2-(Bromomethyl)-5-Chloropyrazine
CAS No.	1433707-80-2
Molecular Formula	C5H4BrClN2
Molecular Weight	207.46 g/mol
Synonyms	5-Chloro-2-(bromomethyl)pyrazine; 2-Bromomethyl-5-chloropyrazine; 5-Chloro-2-pyrazinemethyl bromide; (5-Chloropyrazin-2-yl)methyl bromide; 1433707-80-2; Bromomethyl chloropyrazine
EINECS	Contact for details

Quality Control

Every batch of 2-(Bromomethyl)-5-Chloropyrazine is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance for research and scale-up applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.