Description

1-(1-Methylpiperidin-3-Yl)Piperazin-2-One Dihydrochloride is a high-purity, pharmaceutically relevant building block and intermediate, essential for modern drug discovery and development. Its core value lies in its role as a versatile scaffold for synthesizing novel compounds targeting a range of therapeutic areas. This compound is primarily needed by research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) for central nervous system (CNS) and other therapeutic agents.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Process Development & Scale-Up: Serves as a critical intermediate for optimizing synthetic routes from laboratory to pilot and commercial manufacturing scales.
• Contract Manufacturing: Supplied to CDMOs for the cGMP production of clinical trial materials and commercial drug substances.
• Biochemical Research: Potential use as a tool compound or precursor in probing biological pathways and enzyme interactions.

Basic Information

Product Name	1-(1-Methylpiperidin-3-Yl)Piperazin-2-One Dihydrochloride
CAS No.	1432678-95-9
Molecular Formula	C10H20Cl2N3O
Molecular Weight	269.19 g/mol
Synonyms	1-(1-Methyl-3-piperidinyl)-2-piperazinone dihydrochloride; 1-(1-Methylpiperidin-3-yl)piperazin-2-one hydrochloride (1:2); 2-Piperazinone, 1-(1-methyl-3-piperidinyl)-, dihydrochloride; 1-(1-Methyl-3-piperidyl)piperazin-2-one dihydrochloride; 1-(1-Methylpiperidin-3-yl)piperazin-2-one dihydrochloride salt
EINECS	Contact for details

Quality Control

Our 1-(1-Methylpiperidin-3-Yl)Piperazin-2-One Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability, consistency, and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.