Description

2,6-Dichloro-3-Methoxypyrazine is a high-purity, versatile heterocyclic building block of significant interest in advanced organic synthesis. Its value lies in its functionalized pyrazine core, which serves as a key intermediate for constructing complex molecules with tailored properties. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery and material science.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents, including herbicides and fungicides, leveraging its halogenated pyrazine structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, such as components for organic light-emitting diodes (OLEDs) or conductive polymers.
• Flavor & Fragrance Chemistry: Acts as a synthetic intermediate for creating complex aroma chemicals, given the importance of methoxypyrazines in sensory profiles.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical manufacturing.

Basic Information

Product Name	2,6-Dichloro-3-Methoxypyrazine
CAS No.	1430460-52-8
Molecular Formula	C5H4Cl2N2O
Molecular Weight	179.00 g/mol
Synonyms	3-Methoxy-2,6-dichloropyrazine; 2,6-Dichloro-3-methoxypyrazine; Pyrazine, 2,6-dichloro-3-methoxy-; 2,6-Dichloro-3-pyrazinyl methyl ether; 3-Methoxy-2,6-dichloro-1,4-diazine
EINECS	Contact for details

Quality Control

Our 2,6-Dichloro-3-Methoxypyrazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.