Description

tert-Butyl 4-(4-Bromo-2-Chlorophenyl)Piperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a halogenated aromatic piperazine core. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in central nervous system (CNS) and oncology drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• API Development: Integral in the development and scale-up processes for new active pharmaceutical ingredients (APIs).
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis for clients.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening in drug discovery.
• Chemical Biology Probes: Used to create tool compounds for investigating biological pathways and target validation.

Basic Information

Product Name	tert-Butyl 4-(4-Bromo-2-Chlorophenyl)Piperazine-1-Carboxylate
CAS No.	1429891-40-6
Molecular Formula	C15H20BrClN2O2
Molecular Weight	375.69 g/mol
Synonyms	1-Boc-4-(4-Bromo-2-chlorophenyl)piperazine; tert-Butyl 4-(4-bromo-2-chlorophenyl)-1-piperazinecarboxylate; 4-(4-Bromo-2-chlorophenyl)-N-Boc-piperazine; 1-(tert-Butoxycarbonyl)-4-(4-bromo-2-chlorophenyl)piperazine; 4-(4-Bromo-2-chlorophenyl)piperazine-1-carboxylic acid tert-butyl ester; BOC-4-(4-Bromo-2-Chlorophenyl)Piperazine; 1429891-40-6
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 4-(4-Bromo-2-Chlorophenyl)Piperazine-1-Carboxylate adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to reliable supply and batch-to-batch reproducibility supports your critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.