Description

Rel-(7R,8Ar)-Octahydropyrrolo[1,2-A]Pyrazin-7-Ol CAS NO 1429296-98-9 is a high-purity, stereochemically defined heterocyclic compound belonging to the fused pyrrolopyrazine class. This compound serves as a critical chiral building block and advanced pharmaceutical intermediate for the synthesis of complex active molecules. It is primarily needed by pharmaceutical R&D organizations and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in areas requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the research and development of novel drug candidates.
• API Synthesis: Used in the construction of complex Active Pharmaceutical Ingredients (APIs), especially those targeting the central nervous system (CNS) or infectious diseases.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor in stereoselective chemical transformations.
• Bioconjugation & Probe Development: Potential use in creating labeled compounds or probes for biochemical and diagnostic applications.
• Fine Chemical Production: Serves as a high-value starting material for custom synthesis and contract manufacturing organizations (CMOs).

Basic Information

Product Name	Rel-(7R,8Ar)-Octahydropyrrolo[1,2-A]Pyrazin-7-Ol
CAS No.	1429296-98-9
Molecular Formula	C8H14N2O
Molecular Weight	154.21 g/mol
Synonyms	(7R,8aR)-Octahydro-1H-pyrrolo[1,2-a]pyrazin-7-ol; rel-(7R,8aR)-Octahydropyrrolo[1,2-a]pyrazin-7-ol; Pyrrolo[1,2-a]pyrazin-7-ol, octahydro-, (7R,8aR)-rel-; (7R,8aR)-rel-Octahydro-1H-pyrrolo[1,2-a]pyrazin-7-ol; Fused pyrrolopyrazine alcohol; Chiral pyrrolopyrazine derivative; Pharmaceutical intermediate 1429296-98-9
EINECS	Contact for details

Quality Control

Our Rel-(7R,8Ar)-Octahydropyrrolo[1,2-A]Pyrazin-7-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for pharmaceutical development. Certificates of Analysis (COA) detailing identity, purity, and specific tests are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and may require storage under an inert atmosphere for long-term preservation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.