Description

(S)-4-(2,4-Dimethoxybenzyl)-3-Methylpiperazin-2-One is a high-purity chiral piperazinone derivative, a key advanced pharmaceutical intermediate (API) and building block for sophisticated organic synthesis. Its value lies in its defined stereochemistry and functionalized structure, enabling the development of targeted bioactive molecules. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries, particularly for projects involving chiral amine synthesis and the creation of novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and oncology drug discovery programs.
• Asymmetric Synthesis: Serves as a versatile chiral scaffold and ligand precursor in catalytic asymmetric reactions to create enantiomerically pure compounds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for developing new therapeutic agents.
• Agrochemical Development: Employed as an intermediate in the synthesis of novel, high-value pesticides and herbicides requiring specific stereochemistry.
• Fine Chemical Synthesis: A valuable starting material for synthesizing complex, high-purity specialty chemicals for various industrial applications.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploratory research in organic and medicinal chemistry.

Basic Information

Item	Detail
Product Name	(S)-4-(2,4-Dimethoxybenzyl)-3-Methylpiperazin-2-One
CAS No.	1427063-32-8
Molecular Formula	C15H22N2O3
Molecular Weight	278.35 g/mol
Synonyms	(S)-4-(2,4-Dimethoxybenzyl)-3-methyl-2-oxopiperazine; (S)-3-Methyl-4-(2,4-dimethoxybenzyl)piperazin-2-one; (S)-4-(2,4-Dimethoxybenzyl)-3-methylpiperazin-2-one; (S)-enantiomer of 4-(2,4-Dimethoxybenzyl)-3-methylpiperazin-2-one; (2S)-4-[(2,4-Dimethoxyphenyl)methyl]-3-methylpiperazin-2-one; Chiral 3-methylpiperazin-2-one derivative; (S)-DMB-Methylpiperazinone
EINECS	Contact for details

Quality Control

Our (S)-4-(2,4-Dimethoxybenzyl)-3-Methylpiperazin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.