Description

1-(4-Bromo-3-Chlorophenyl)-4-Methylpiperazine is a high-purity, advanced pharmaceutical intermediate characterized by its halogenated aromatic and piperazine structure. This compound is critical for medicinal chemistry research and development, serving as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D laboratories and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new therapeutic agents or functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Agrochemical Development: Serves as a building block for creating novel pesticides and herbicides due to its halogenated aromatic system.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and material science applications.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target identification.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	1-(4-Bromo-3-Chlorophenyl)-4-Methylpiperazine
CAS No.	1426958-37-3
Molecular Formula	C11H14BrClN2
Molecular Weight	289.60 g/mol
Synonyms	4-Methyl-1-(4-bromo-3-chlorophenyl)piperazine; 1-(4-Bromo-3-chlorophenyl)-4-methylpiperazine; 4-Bromo-3-chloro-N-methylpiperazin-1-ylbenzene; 4-Methyl-1-(4-bromo-3-chloro-phenyl)piperazine; 4'-Bromo-3'-chloro-4-methylpiperazin-1-ylbenzene; (4-Bromo-3-chlorophenyl)(4-methylpiperazin-1-yl)methanone (Note: Verify specific isomer); 4-Methyl-1-(4-bromo-3-chloro-phenyl)-piperazine
EINECS	Contact for details

Quality Control

Our 1-(4-Bromo-3-Chlorophenyl)-4-Methylpiperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements or regulatory standards for research use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.