Description

1-(4-Bromo-3-Chlorophenyl)-4-Ethylpiperazine is a high-purity, advanced pharmaceutical intermediate characterized by its piperazine core substituted with a halogenated phenyl ring. This compound is critically important for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and receptor-targeted drug discovery. It is primarily required by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel drug candidates, especially those targeting neurological and psychiatric disorders.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemists to explore structure-activity relationships (SAR) and develop new chemical entities.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the production route for specific APIs where the bromo-chloro-phenyl-piperazine moiety is a core pharmacophore.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Biochemical Tool Compound: Utilized in pharmacological studies to investigate receptor binding and enzyme inhibition assays.

Basic Information

Product Name	1-(4-Bromo-3-Chlorophenyl)-4-Ethylpiperazine
CAS No.	1426958-32-8
Molecular Formula	C12H16BrClN2
Molecular Weight	303.63 g/mol
Synonyms	4-Ethyl-1-(4-bromo-3-chlorophenyl)piperazine; 1-(4-Bromo-3-chlorophenyl)-4-ethyl-piperazine; 4-Bromo-3-chloro-N-ethylpiperazine; 4-Ethylpiperazine-1-(4-bromo-3-chlorobenzene); (4-Bromo-3-chlorophenyl)-4-ethylpiperazine; 4-Bromo-3-chloro-1-(4-ethylpiperazin-1-yl)benzene
EINECS	Contact for details

Quality Control

Our 1-(4-Bromo-3-Chlorophenyl)-4-Ethylpiperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic). Keep away from strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.