Description

Amino-Peg7-Alcohol CAS NO 1425973-14-3 is a heterobifunctional polyethylene glycol (PEG) derivative featuring a primary amine group and a terminal hydroxyl group, separated by a heptaethylene glycol spacer. This bifunctionality is critical for creating stable, hydrophilic linkers in bioconjugation and pharmaceutical development, improving the solubility and pharmacokinetic profiles of therapeutic agents. It is an essential building block for researchers and manufacturers in the biopharmaceutical, diagnostics, and advanced materials sectors who require precise, high-purity PEGylation reagents.

Application

• Bioconjugation and PEGylation: Serves as a versatile linker for attaching drugs, proteins, peptides, or fluorescent dyes, enhancing their stability and circulation time.
• Antibody-Drug Conjugate (ADC) Development: Used to construct hydrophilic, cleavable, or non-cleavable linkers between cytotoxic payloads and monoclonal antibodies.
• Diagnostic Reagent Synthesis: Functionalizes surfaces of nanoparticles, microspheres, or biosensors with amine-reactive chemistry for assay development.
• Hydrogel and Biomaterial Fabrication: Acts as a cross-linking agent or hydrophilic modifier in the synthesis of biocompatible polymers and scaffolds for tissue engineering.
• Solubility Enhancer for APIs: Conjugated to poorly water-soluble active pharmaceutical ingredients (APIs) to improve their aqueous solubility and bioavailability.
• Surface Functionalization: Used to create amine-terminated self-assembled monolayers (SAMs) on gold or silicon surfaces for further chemical modification.

Basic Information

Product Name	Amino-Peg7-Alcohol
CAS No.	1425973-14-3
Molecular Formula	C16H35NO9
Molecular Weight	385.45 g/mol
Synonyms	2,5,8,11,14,17,20-Heptaoxadocosan-22-ol, 21-amino-; 21-Amino-3,6,9,12,15,18,21-heptaoxahenicosan-1-ol; 15-Amino-4,7,10,13-tetraoxapentadecan-1-ol (PEG7 derivative); NH2-PEG7-OH; Amine-PEG7-alcohol; H2N-PEG7-OH; α-Amino-ω-hydroxy-hepta(ethylene glycol); Amino heptaethylene glycol
EINECS	Contact for details

Quality Control

Every batch of Amino-Peg7-Alcohol is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure it meets the high-purity standards required for sensitive bioconjugation work. We provide Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity, identity, and functional group content. Our quality commitment supports applications in GMP and research environments where reproducibility and traceability are paramount.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This compound is hygroscopic (moisture-sensitive). For long-term storage under inert atmosphere (argon or nitrogen) is recommended to prevent oxidation and maintain optimal purity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Amine Value (Titration)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.