Description

2-Bromo-5H-Pyrrolo[2,3-B]Pyrazine-7-Carboxylic Acid is a high-value, heterocyclic building block of significant interest in advanced organic synthesis. This compound is crucial for medicinal chemistry research and development, serving as a key precursor for the construction of complex molecular architectures. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and oncology research programs.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Chemical Biology Probes: Serves as a precursor for developing molecular probes to study biological pathways and target validation.
• Agrochemical Synthesis: Potential intermediate in the development of new crop protection agents with specific biological activity.
• Material Science Precursor: Can be utilized in the synthesis of organic electronic materials and specialty polymers.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	2-Bromo-5H-Pyrrolo[2,3-B]Pyrazine-7-Carboxylic Acid
CAS No.	1422772-78-8
Molecular Formula	C7H4BrN3O2
Molecular Weight	242.03 g/mol
Synonyms	2-Bromo-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid; 7-Bromo-3H-pyrrolo[2,3-b]pyrazine-5-carboxylic acid; 2-Bromo-7-carboxy-5H-pyrrolo[2,3-b]pyrazine; 2-Bromopyrrolo[2,3-b]pyrazine-7-carboxylic acid; Pyrrolo[2,3-b]pyrazine-7-carboxylic acid, 2-bromo-; 1422772-78-8
EINECS	Contact for details

Quality Control

Our 2-Bromo-5H-Pyrrolo[2,3-B]Pyrazine-7-Carboxylic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry. Certificates of Analysis (COA) are available for every batch upon request, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.