Description

Ethyl 5,6,7,8-Tetrahydro-[1,2,4]Triazolo[1,5-A]Pyrazine-2-Carboxylate (Wx141170) is a high-purity, advanced pharmaceutical intermediate belonging to the fused triazolopyrazine class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily sought after by research institutions, custom synthesis houses, and pharmaceutical manufacturers engaged in the development of new drug candidates.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug molecules, especially for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop compounds with improved efficacy and safety profiles.
• Custom Synthesis & Contract Manufacturing: Serves as a specialized starting material for the custom synthesis of complex organic molecules on a commercial scale.
• Chemical Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Agrochemical Research: Potential application as an intermediate in the discovery of new agrochemicals, such as herbicides or insecticides, leveraging its heterocyclic core.

Basic Information

Product Name	Ethyl 5,6,7,8-Tetrahydro-[1,2,4]Triazolo[1,5-A]Pyrazine-2-Carboxylate (Wx141170)
CAS No.	1422344-37-3
Molecular Formula	C8H12N4O2
Molecular Weight	196.21 g/mol
Synonyms	Ethyl 5,6,7,8-tetrahydro[1,2,4]triazolo[1,5-a]pyrazine-2-carboxylate; 1,2,4-Triazolo[1,5-a]pyrazine-2-carboxylic acid, 5,6,7,8-tetrahydro-, ethyl ester; WX-141170; WX141170; Ethyl tetrahydrotriazolopyrazinecarboxylate; 1422344-37-3; 5,6,7,8-Tetrahydro-[1,2,4]triazolo[1,5-a]pyrazine-2-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 5,6,7,8-Tetrahydro-[1,2,4]Triazolo[1,5-A]Pyrazine-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.