Description

Ethyl 5,6,7,8-Tetrahydro-4H-[1,2,3]Triazolo[1,5-A][1,4]Diazepine-3-Carboxylate Hydrochloride (Wx140989) is a high-purity, advanced pharmaceutical intermediate belonging to the triazolodiazepine chemical class. This compound is of significant value for research and development in medicinal chemistry, particularly in the synthesis of novel bioactive molecules targeting the central nervous system. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel triazolodiazepine-based active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new therapeutic candidates.
• CNS Drug Development: Serves as a core scaffold for researching potential treatments for neurological and psychiatric disorders.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Chemical Biology Probes: Utilized in the development of molecular probes to study biological pathways and receptor interactions.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) producing bespoke compounds for client research programs.

Basic Information

Product Name	Ethyl 5,6,7,8-Tetrahydro-4H-[1,2,3]Triazolo[1,5-A][1,4]Diazepine-3-Carboxylate Hydrochloride (Wx140989)
CAS No.	1422344-35-1
Molecular Formula	C11H16ClN5O2
Molecular Weight	285.73 g/mol
Synonyms	Ethyl 4,5,6,7-tetrahydro-3H-[1,2,3]triazolo[1,5-a][1,4]diazepine-3-carboxylate hydrochloride; WX-140989; Wx140989; 1,2,3-Triazolo[1,5-a][1,4]diazepine-3-carboxylic acid, 5,6,7,8-tetrahydro-4H-, ethyl ester, hydrochloride; Ethyl 5,6,7,8-tetrahydro-4H-[1,2,3]triazolo[1,5-a][1,4]diazepine-3-carboxylate HCl
EINECS	Contact for details

Quality Control

Our Ethyl 5,6,7,8-Tetrahydro-4H-[1,2,3]Triazolo[1,5-A][1,4]Diazepine-3-Carboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.