Description

1-(5-Fluoro-2-Methoxyphenyl)Piperazine Hcl is a high-purity, advanced pharmaceutical intermediate and research chemical. This compound is critical for the development of novel active pharmaceutical ingredients (APIs), particularly in the fields of central nervous system (CNS) and psychiatric therapeutics. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for CNS-targeting molecules.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in API manufacturing.
• Biochemical Research: Employed in pharmacological studies to investigate receptor binding and enzyme inhibition mechanisms.
• Fine Chemical Synthesis: A versatile precursor for the preparation of more complex piperazine-derived specialty chemicals.

Basic Information

Product Name	1-(5-Fluoro-2-Methoxyphenyl)Piperazine Hydrochloride
CAS No.	1421604-76-3
Molecular Formula	C11H15FN2O • HCl
Molecular Weight	246.71 g/mol
Synonyms	1-(5-Fluoro-2-methoxyphenyl)piperazine hydrochloride; 5-Fluoro-2-methoxyphenylpiperazine HCl; 2-Methoxy-5-fluorophenylpiperazine hydrochloride; 1-(5-Fluoro-2-methoxyphenyl)piperazine monohydrochloride; 1421604-76-3; 5-Fluoro-2-methoxyphenylpiperazine monohydrochloride; 1-(5-Fluoro-2-methoxyphenyl)piperazine HCl salt
EINECS	Contact for details

Quality Control

Our 1-(5-Fluoro-2-Methoxyphenyl)Piperazine Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) documenting full specifications are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.