Description

2-Methyl-3-(Piperidin-4-Yloxy)-Pyrazine Hydrochloride is a high-purity organic salt compound with the CAS number 1420961-37-0, serving as a critical advanced intermediate in modern pharmaceutical synthesis. Its unique molecular structure, featuring a pyrazine core linked to a piperidine moiety, makes it a valuable building block for constructing complex active pharmaceutical ingredients (APIs). This compound is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within central nervous system (CNS) and other specialty drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and production of novel drug candidates.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural scaffold for constructing complex molecules with potential therapeutic activity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for cGMP-scale synthesis.
• Biochemical Research: Employed as a tool compound in biochemical assays and target validation studies.
• Reference Standard: Sourced for analytical purposes, including method development and quality control as a high-purity reference material.

Basic Information

Item	Details
Product Name	2-Methyl-3-(Piperidin-4-Yloxy)-Pyrazine Hydrochloride
CAS No.	1420961-37-0
Molecular Formula	C10H16ClN3O
Molecular Weight	229.71 g/mol
Synonyms	2-Methyl-3-(4-piperidinyloxy)pyrazine hydrochloride; 3-((Piperidin-4-yl)oxy)-2-methylpyrazine hydrochloride; 2-Methyl-3-(piperidin-4-yloxy)pyrazine HCl; 1420961-37-0; 4-((2-Methylpyrazin-3-yl)oxy)piperidine hydrochloride; Pyrazine, 2-methyl-3-(4-piperidinyloxy)-, hydrochloride; 2-Methyl-3-(4-piperidyloxy)pyrazine hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Methyl-3-(Piperidin-4-Yloxy)-Pyrazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical R&D and manufacturing. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.