Description

1-[(5-Bromo-2-Thienyl)Sulfonyl]-Piperazine is a high-purity, advanced pharmaceutical intermediate characterized by its unique sulfonyl-piperazine-thiophene scaffold. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel, targeted therapeutic agents. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new chemical entities, particularly for central nervous system (CNS) and oncology drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel small-molecule drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• Protease Inhibitor Synthesis: Serves as a core structural component in the design of potential protease inhibitors.
• Kinase Inhibitor Development: Employed in the synthesis of candidate molecules targeting various kinase enzymes.
• Chemical Biology Probes: Utilized to create tool compounds for studying biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke synthesis projects requiring this specific brominated heterocyclic sulfonamide.

Basic Information

Product Name	1-[(5-Bromo-2-Thienyl)Sulfonyl]-Piperazine
CAS No.	1420864-59-0
Molecular Formula	C9H11BrN2O2S2
Molecular Weight	323.23 g/mol
Synonyms	1-(5-Bromo-2-thienylsulfonyl)piperazine; 1-(5-Bromothiophene-2-sulfonyl)piperazine; 5-Bromo-2-thiophenesulfonamide, N-(1-piperazinyl)-; Piperazine, 1-[(5-bromo-2-thienyl)sulfonyl]-; 1420864-59-0; 5-Bromo-2-thiophenesulfonyl piperazine; 1-(5-Bromo-thiophene-2-sulfonyl)-piperazine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch of 1-[(5-Bromo-2-Thienyl)Sulfonyl]-Piperazine is analyzed to confirm identity, purity, and impurity profile. We adhere to strict in-house specifications suitable for research and development use. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.