Description

tert-Butyl ((1-(1,1-Dioxidobenzo[D]Isothiazol-3-Yl)Piperidin-4-Yl)Methyl)Carbamate is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, particularly for projects targeting neurological and inflammatory pathways. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the production of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those with sulfonamide or benzisothiazole dioxide scaffolds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for central nervous system (CNS) and anti-inflammatory targets.
• API Development: Serves as a critical precursor in the multi-step synthesis of complex small molecule APIs under current Good Manufacturing Practice (cGMP) conditions.
• Bioconjugation & Probe Synthesis: The carbamate and piperidine functionalities make it suitable for creating chemical probes or conjugates for biological assay development.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and commercial production of specialty pharmaceuticals.

Basic Information

Product Name	tert-Butyl ((1-(1,1-Dioxidobenzo[D]Isothiazol-3-Yl)Piperidin-4-Yl)Methyl)Carbamate
CAS No.	1420820-73-0
Molecular Formula	C19H27N3O4S
Molecular Weight	393.50 g/mol
Synonyms	Boc-4-((1,1-Dioxido-3-benzisothiazolyl)aminomethyl)piperidine; tert-Butyl N-[[1-(1,1-dioxo-1,2-benzisothiazol-3-yl)piperidin-4-yl]methyl]carbamate; 1,1-Dioxobenzo[d]isothiazol-3-yl-piperidin-4-ylmethyl-carbamic acid tert-butyl ester; 4-[[(tert-Butoxycarbonyl)amino]methyl]-1-(1,1-dioxido-1,2-benzisothiazol-3-yl)piperidine; 1420820-73-0; UNII-7J3K4F8K4R
EINECS	Contact for details

Quality Control

Our tert-Butyl ((1-(1,1-Dioxidobenzo[D]Isothiazol-3-Yl)Piperidin-4-Yl)Methyl)Carbamate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your internal quality standards and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged operations to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.