Description

1-Bromo-3-Morpholinoimidazo[1,5-A]Pyrazin-8-Amine is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for oncology and anti-inflammatory targets.
• Kinase Inhibitor Development: Serves as a core scaffold for the research and development of potent and selective kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs in academic and industrial R&D labs.
• Chemical Biology Probes: Employed in the creation of tool compounds for studying specific biological pathways and target validation.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.
• Library Synthesis: Used to generate diverse chemical libraries for high-throughput screening in drug discovery campaigns.

Basic Information

Product Name	1-Bromo-3-Morpholinoimidazo[1,5-A]Pyrazin-8-Amine
CAS No.	1419222-67-5
Molecular Formula	C10H12BrN5O
Molecular Weight	298.14 g/mol
Synonyms	1-Bromo-3-morpholin-4-ylimidazo[1,5-a]pyrazin-8-amine; 1-Bromo-3-(morpholin-4-yl)imidazo[1,5-a]pyrazin-8-amine; Imidazo[1,5-a]pyrazin-8-amine, 1-bromo-3-morpholino-; 1419222-67-5; 1-Bromo-3-morpholinoimidazo[1,5-a]pyrazin-8-amine; 3-Morpholino-1-bromoimidazo[1,5-a]pyrazin-8-amine
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-Morpholinoimidazo[1,5-A]Pyrazin-8-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and stringent in-process controls guarantees a reliable supply of this high-value intermediate for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.