Description

1-Boc-4-(Ethoxymethyl)Piperidin-4-Ol is a high-purity, protected piperidine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is essential for medicinal chemists and process development scientists working on active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where precise stereochemistry and functional group manipulation are required.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its functionalized piperidine core.
• Chemical Biology & Proteomics: Employed as a scaffold or linker in the design of molecular probes and activity-based protein profiling (ABPP) reagents.
• Peptidomimetics: Serves as a constrained, non-natural amino acid analog for creating stable peptide-like structures with enhanced pharmacological properties.
• Ligand & Catalyst Development: Utilized in the preparation of chiral ligands for asymmetric catalysis or as a precursor for metal-organic frameworks (MOFs).
• Academic & Contract Research: A valuable reagent for methodology development and exploring new synthetic routes in academic and industrial R&D laboratories.

Basic Information

Product Name	1-Boc-4-(Ethoxymethyl)Piperidin-4-Ol
CAS No.	1419101-09-9
Molecular Formula	C13H25NO4
Molecular Weight	259.34 g/mol
Synonyms	4-(Ethoxymethyl)-4-hydroxy-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; tert-Butyl 4-(ethoxymethyl)-4-hydroxypiperidine-1-carboxylate; 1-Boc-4-(ethoxymethyl)-4-hydroxypiperidine; 4-Hydroxy-4-(ethoxymethyl)piperidine-1-carboxylic acid tert-butyl ester; N-Boc-4-(ethoxymethyl)-4-hydroxypiperidine; 1-(tert-Butoxycarbonyl)-4-(ethoxymethyl)piperidin-4-ol; Piperidine-1-carboxylic acid, 4-(ethoxymethyl)-4-hydroxy-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 1-Boc-4-(Ethoxymethyl)Piperidin-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider using desiccants or storing under an inert atmosphere to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.