Description

(S)-4-tert-Butylcarbonyl-2-Methylpiperazine is a high-purity chiral piperazine derivative, a crucial building block in modern pharmaceutical synthesis. Its value lies in its role as a key intermediate for constructing complex molecules with specific stereochemistry, essential for developing active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• API Development: Used in constructing the core scaffold of potential Active Pharmaceutical Ingredients requiring specific (S)-configuration.
• Asymmetric Synthesis: Serves as a versatile chiral auxiliary or ligand precursor in catalytic asymmetric reactions.
• Agrochemical Research: Employed in the development of advanced, stereospecific pesticides and herbicides.
• Chemical Biology: Useful as a building block for creating molecular probes and tool compounds for biological target validation.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	(S)-4-tert-Butylcarbonyl-2-Methylpiperazine
CAS No.	1419100-97-2
Molecular Formula	C10H20N2O
Molecular Weight	184.28 g/mol
Synonyms	(S)-1-tert-Butoxycarbonyl-2-methylpiperazine; (S)-2-Methyl-1-(tert-butoxycarbonyl)piperazine; (S)-N-Boc-2-methylpiperazine; (S)-1-Boc-2-methylpiperazine; (S)-2-Methylpiperazine-1-carboxylic acid tert-butyl ester; (S)-tert-Butyl 2-methylpiperazine-1-carboxylate; (2S)-2-Methyl-1-[(2-methylpropan-2-yl)oxycarbonyl]piperazine
EINECS	Contact for details

Quality Control

Our (S)-4-tert-Butylcarbonyl-2-Methylpiperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.