Description

(S)-Benzyl 2-(8-Chloroimidazo[1,5-A]Pyrazin-3-Yl)Pyrrolidine-1-Carboxylate is a high-purity chiral building block and advanced pharmaceutical intermediate designed for complex organic synthesis. This compound is critical for medicinal chemistry research and development, particularly in the creation of novel therapeutic agents targeting specific biological pathways. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and contract research organizations (CROs) engaged in the synthesis of active pharmaceutical ingredients (APIs) and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of potential drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery projects.
• API Development: Serves as a critical building block in the process development and scale-up of new active pharmaceutical ingredients (APIs).
• Chemical Biology Probes: Utilized in the development of specialized chemical probes for studying enzyme function and biological target engagement.
• Asymmetric Synthesis: Employed in catalytic and stoichiometric asymmetric synthesis due to its defined stereochemistry at the pyrrolidine center.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and cGMP production.

Basic Information

Item	Detail
Product Name	(S)-Benzyl 2-(8-Chloroimidazo[1,5-A]Pyrazin-3-Yl)Pyrrolidine-1-Carboxylate
CAS No.	1418307-18-2
Molecular Formula	C18H17ClN4O2
Molecular Weight	356.81 g/mol
Synonyms	(S)-Benzyl 2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate; 1-Pyrrolidinecarboxylic acid, 2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)-, phenylmethyl ester, (2S)-; (S)-1-((Benzyloxy)carbonyl)-2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)pyrrolidine; (S)-Cbz-2-(8-Chloroimidazo[1,5-a]pyrazin-3-yl)pyrrolidine; (S)-8-Chloro-3-(1-((benzyloxy)carbonyl)pyrrolidin-2-yl)imidazo[1,5-a]pyrazine; 1418307-18-2; Chiral Imidazopyrazine Derivative
EINECS	Contact for details

Quality Control

Our (S)-Benzyl 2-(8-Chloroimidazo[1,5-A]Pyrazin-3-Yl)Pyrrolidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with research and development grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions or inert atmosphere to maintain stability. For long-term storage, consider storage under an inert gas such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.