Description

2-Chloro-1-(3'-Methyl-2,3,5,6-tetrahydro-[1,2']bipyrazinyl-4-yl)-ethanone is a high-purity, advanced pharmaceutical intermediate characterized by its unique bipyrazinyl core structure. This compound matters as a critical building block in the synthesis of novel, complex molecules, particularly for drug discovery programs targeting central nervous system and metabolic disorders. Pharmaceutical R&D laboratories and fine chemical manufacturers need this precise intermediate to enable efficient and scalable routes for producing active pharmaceutical ingredients (APIs) with high stereochemical and chemical purity.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs), especially for neurological and metabolic disease targets.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore novel pharmacophores based on the bipyrazinyl scaffold.
• Process Chemistry Development: Serves as a critical starting material or intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development of proprietary compounds for clinical trials.
• Agrochemical Research: Potential application as an intermediate in the synthesis of novel crop protection agents and pesticides.
• Academic & Institutional Research: Utilized in universities and research institutes for fundamental studies in heterocyclic chemistry and synthetic methodology.

Basic Information

Product Name	2-Chloro-1-(3'-Methyl-2,3,5,6-tetrahydro-[1,2']bipyrazinyl-4-yl)-ethanone
CAS No.	1417794-34-3
Molecular Formula	C12H15ClN4O
Molecular Weight	266.73 g/mol
Synonyms	2-Chloro-1-(3'-methyl-2,3,5,6-tetrahydro-[1,2'-bipyrazin]-4-yl)ethan-1-one; 4-Acetyl-3'-methyl-2,3,5,6-tetrahydro-1,2'-bipyrazine-2'-carbonitrile (related precursor); 1-(3'-Methyl-2,3,5,6-tetrahydro-[1,2']bipyrazinyl-4-yl)-2-chloroethanone; CAS 1417794-34-3; Bipyrazinyl Ethanone Derivative; Chloroacetyl Bipyrazinyl Intermediate
EINECS	Contact for details

Quality Control

Our 2-Chloro-1-(3'-Methyl-2,3,5,6-tetrahydro-[1,2']bipyrazinyl-4-yl)-ethanone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements, including development-grade and GMP-grade material upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.