Description

1-(2-Methoxy-4-Nitro-Phenyl)-Piperazine Hydrochloride is a high-purity, synthetically derived organic compound that serves as a critical building block in advanced pharmaceutical research and development. Its unique molecular structure, featuring a nitro-substituted aromatic ring linked to a piperazine moiety, makes it a versatile intermediate for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is essential for medicinal chemists and process development scientists working in the pharmaceutical, agrochemical, and fine chemical industries, particularly in the creation of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Agrochemical Synthesis: Serves as a building block for developing advanced crop protection agents and pesticides.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and other performance materials requiring nitro-aromatic chemistry.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis and scale-up projects under cGMP conditions.
• Academic & Institutional Research: Used in university and government laboratories for biochemical and pharmacological studies.

Basic Information

Product Name	1-(2-Methoxy-4-Nitro-Phenyl)-Piperazine Hydrochloride
CAS No.	1417793-92-0
Molecular Formula	C11H16ClN3O3
Molecular Weight	273.72 g/mol
Synonyms	1-(2-Methoxy-4-nitrophenyl)piperazine hydrochloride; 2-Methoxy-4-nitro-1-piperazin-1-ylbenzene hydrochloride; 4-Nitro-2-methoxyphenylpiperazine hydrochloride; Piperazine, 1-(2-methoxy-4-nitrophenyl)-, hydrochloride (1:1); UNII-9Z6X2N5Q6F; 9Z6X2N5Q6F
EINECS	Contact for details

Quality Control

Our 1-(2-Methoxy-4-Nitro-Phenyl)-Piperazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) are provided with every shipment, detailing all specifications and test results. We support development and commercial projects with material suitable for research use through to cGMP-grade production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.