Description

1-(6-Nitro-Quinoxalin-2-Yl)-Piperidin-4-Ol is a high-purity, advanced pharmaceutical intermediate characterized by its fused quinoxaline-piperidine heterocyclic structure. This compound is of significant commercial interest for its role as a key building block in the research and development of novel therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in synthesizing complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of targeted small-molecule drugs, especially kinase inhibitors and other enzyme modulators.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Used in vitro and in vivo to study biological pathways and validate novel drug targets.
• Agrochemical Research: Potential application in the development of new active ingredients for crop protection, leveraging its heterocyclic core.
• Material Science: Exploration as an organic precursor for functional materials, such as ligands for catalysts or components in organic electronics.

Basic Information

Product Name	1-(6-Nitro-Quinoxalin-2-Yl)-Piperidin-4-Ol
CAS No.	1417793-14-6
Molecular Formula	C₁₃H₁₄N₄O₃
Molecular Weight	274.28 g/mol
Synonyms	1-(6-Nitroquinoxalin-2-yl)piperidin-4-ol; 4-Piperidinol, 1-(6-nitro-2-quinoxalinyl)-; 1-(6-Nitro-quinoxalin-2-yl)-piperidin-4-ol; 1-(6-Nitroquinoxalin-2-yl)piperidin-4-ol; 1417793-14-6; 6-Nitro-2-(4-hydroxypiperidin-1-yl)quinoxaline; 2-(4-Hydroxypiperidin-1-yl)-6-nitroquinoxaline
EINECS	Contact for details

Quality Control

Our production of 1-(6-Nitro-Quinoxalin-2-Yl)-Piperidin-4-Ol adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry, inert conditions to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.