Description

(1S,6R)-3-Boc-3,7-Diazabicyclo[4.2.0]Octane CAS NO 1417789-49-1 is a high-purity, advanced pharmaceutical intermediate featuring a protected diazabicyclic core structure. This compound is a critical chiral building block for the synthesis of complex active pharmaceutical ingredients (APIs), offering precise stereochemical control. It is primarily utilized by research and development teams in the pharmaceutical and biotechnology industries for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates, particularly those targeting the central nervous system.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities.
• Process Chemistry Development: Serves as a starting material or intermediate in the scale-up and route development for API manufacturing.
• Protease Inhibitor Synthesis: Potential building block for the development of protease inhibitors due to its constrained bicyclic amine structure.
• Ligand and Catalyst Preparation: Can be utilized to create novel chiral ligands or organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Employed in the construction of molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	(1S,6R)-3-Boc-3,7-Diazabicyclo[4.2.0]Octane
CAS No.	1417789-49-1
Molecular Formula	C12H22N2O2
Molecular Weight	226.32 g/mol
Synonyms	(1S,6R)-3-(tert-Butoxycarbonyl)-3,7-diazabicyclo[4.2.0]octane; tert-Butyl (1S,6R)-3,7-diazabicyclo[4.2.0]octane-3-carboxylate; (1S,6R)-3-Boc-3,7-diazabicyclo[4.2.0]octane; Bicyclo[4.2.0]octane-3-carboxylic acid, 3,7-diaza-, 1,1-dimethylethyl ester, (1S,6R)-; (1S,6R)-3-Boc-7-aza-3-azabicyclo[4.2.0]octane
EINECS	Contact for details

Quality Control

Our (1S,6R)-3-Boc-3,7-Diazabicyclo[4.2.0]Octane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.