Description

4-Formylpiperazine-1-Carboximidamide Sulfate is a high-purity, specialized organic salt with significant utility as a key synthetic intermediate in advanced pharmaceutical research and development. Its unique molecular structure, featuring both formyl and carboximidamide functional groups on a piperazine backbone, makes it a valuable building block for constructing complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in areas like kinase inhibitors and other targeted therapies.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new chemical entities with optimized biological activity.
• Process Chemistry & Scale-up: Serves as a starting material or intermediate in the development and optimization of scalable, GMP-compliant manufacturing routes for APIs.
• Bioconjugation & Probe Development: The reactive functional groups can be utilized for creating chemical probes, diagnostic agents, or antibody-drug conjugates (ADCs) in biochemical research.
• Chemical Library Synthesis: Employed in combinatorial chemistry to generate diverse libraries of compounds for biological screening and hit identification.

Basic Information

Product Name	4-Formylpiperazine-1-Carboximidamide Sulfate
CAS No.	1417567-69-1
Molecular Formula	C7H14N4O • H2SO4 or C7H16N4O5S
Molecular Weight	Contact for details
Synonyms	1-Piperazinecarboximidamide, 4-formyl-, sulfate (1:1); 4-Formylpiperazine-1-carboximidamide hemisulfate; 4-Formyl-N-amidinopiperazine sulfate; 1-Formyl-4-carbamimidoylpiperazine sulfate; 4-Formylpiperazine-1-carboxamidine sulfate; 4-FPC Sulfate; Piperazine-1-carboximidamide, 4-formyl-, sulfate
EINECS	Contact for details

Quality Control

Every batch of 4-Formylpiperazine-1-Carboximidamide Sulfate is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as identity, purity (by HPLC), and impurity profile. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability, consistency, and reliability for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C (refrigerated). Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.