Description

2-Bromo-5H-Pyrrolo[2,3-B]Pyrazin-7-Ylamine is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated pyrrolopyrazine core structure. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel drug candidates. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on oncology, kinase inhibitors, and other targeted therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex small-molecule drugs, particularly kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes to study biological pathways and protein functions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and drug discovery.

Basic Information

Product Name	2-Bromo-5H-Pyrrolo[2,3-B]Pyrazin-7-Ylamine
CAS No.	1416740-17-4
Molecular Formula	C6H5BrN4
Molecular Weight	213.04 g/mol
Synonyms	7-Amino-2-bromo-5H-pyrrolo[2,3-b]pyrazine; 2-Bromo-5H-pyrrolo[2,3-b]pyrazin-7-amine; 2-Bromo-7-amino-5H-pyrrolo[2,3-b]pyrazine; 1416740-17-4; 2-Bromo-7-aminopyrrolo[2,3-b]pyrazine; Pyrrolo[2,3-b]pyrazin-7-amine, 2-bromo-5H-; SCHEMBL21806227; BDBM50389357
EINECS	Contact for details

Quality Control

Our 2-Bromo-5H-Pyrrolo[2,3-B]Pyrazin-7-Ylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your research and development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a dry environment to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.