Description

2-Bromo-7-Nitro-5H-Pyrrolo[2,3-B]Pyrazine is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique fused pyrrolopyrazine core, functionalized with bromo and nitro groups, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, including kinase inhibitors and other biologically relevant small molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Research: Used to develop new active ingredients for crop protection with potential novel modes of action.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for designing molecular probes and tool compounds to study biological pathways.
• Material Science: Potential building block for organic electronic materials and functional dyes due to its electron-deficient aromatic system.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and discovery chemistry projects.
• Custom Synthesis: A starting material for the tailored synthesis of more complex, target-specific molecules for client-directed research.

Basic Information

Product Name	2-Bromo-7-Nitro-5H-Pyrrolo[2,3-B]Pyrazine
CAS No.	1416740-16-3
Molecular Formula	C6H3BrN4O2
Molecular Weight	242.02 g/mol
Synonyms	2-Bromo-7-nitropyrrolo[2,3-b]pyrazine; 5H-Pyrrolo[2,3-b]pyrazine, 2-bromo-7-nitro-; 7-Nitro-2-bromo-5H-pyrrolo[2,3-b]pyrazine; 2-Bromo-7-nitro-5H-pyrrolo[2,3-b]pyrazine; Pyrrolo[2,3-b]pyrazine, 2-bromo-7-nitro-; 1416740-16-3; 2-Br-7-NO2-Pyrrolo[2,3-b]pyrazine
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-7-Nitro-5H-Pyrrolo[2,3-B]Pyrazine is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	Yellow to light brown powder or crystalline solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.