Description

2-Pyrazinecarboxylic Acid, 5-Iodo-, Ethyl Ester is a halogenated pyrazine derivative that serves as a versatile and valuable synthetic intermediate in advanced organic chemistry. Its core value lies in the strategic incorporation of iodine, which provides a reactive handle for further functionalization via cross-coupling reactions, enabling the construction of complex heterocyclic systems. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting heterocyclic scaffolds.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the pyrazine core can impart specific biological activity.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and material science.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Stille couplings.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and dyes.
• Academic & R&D: A valuable reagent for methodological studies and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	2-Pyrazinecarboxylic Acid, 5-Iodo-, Ethyl Ester
CAS No.	1416575-48-8
Molecular Formula	C7H7IN2O2
Molecular Weight	278.05 g/mol
Synonyms	Ethyl 5-iodopyrazine-2-carboxylate; 5-Iodo-2-pyrazinecarboxylic Acid Ethyl Ester; Ethyl 5-iodo-2-pyrazinecarboxylate; 5-Iodopyrazine-2-carboxylic Acid Ethyl Ester; 2-Carbethoxy-5-iodopyrazine; SCHEMBL21821027; AKOS040759045
EINECS	Contact for details

Quality Control

Our 2-Pyrazinecarboxylic Acid, 5-Iodo-, Ethyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.