Description

(S)-3-(Boc-Amino)Piperidine Hydrochloride is a high-purity, chiral piperidine derivative protected with a tert-butoxycarbonyl (Boc) group. This compound serves as a critical chiral building block and intermediate in the synthesis of complex pharmaceutical molecules, particularly those targeting the central nervous system. It is essential for medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries who require enantiomerically pure intermediates for drug discovery and development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of active pharmaceutical ingredients (APIs), especially for neurological and psychiatric disorders.
• Drug Discovery & Medicinal Chemistry: Used as a versatile scaffold for constructing compound libraries and optimizing lead molecules in preclinical research.
• Peptidomimetics Synthesis: Incorporated into peptide analogs to enhance metabolic stability and bioavailability.
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor in stereoselective chemical reactions.
• Contract Manufacturing (CMO/CDMO): Supplied to contract research and manufacturing organizations for custom synthesis projects.
• Academic & Institutional Research: Utilized in university and government labs for chemical biology and synthetic methodology studies.

Basic Information

Product Name	(S)-3-(Boc-Amino)Piperidine Hydrochloride
CAS No.	1416450-55-9
Molecular Formula	C10H21ClN2O2
Molecular Weight	236.74 g/mol
Synonyms	(S)-3-[(tert-Butoxycarbonyl)amino]piperidine hydrochloride; (S)-1-Boc-3-aminopiperidine hydrochloride; (S)-3-Amino-1-Boc-piperidine hydrochloride; (S)-N-Boc-3-aminopiperidine HCl; (S)-3-(tert-Butoxycarbonylamino)piperidine HCl; (S)-3-(Boc-amino)piperidine HCl; tert-Butyl (S)-3-aminopiperidine-1-carboxylate hydrochloride; (3S)-3-[[(1,1-Dimethylethoxy)carbonyl]amino]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-3-(Boc-Amino)Piperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and cGMP applications. A detailed Certificate of Analysis (COA) providing specifications for identity, purity (typically ≥98%), enantiomeric excess (ee), and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity. Allow the container to reach ambient temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.