Description

8-Bromo-4-Chloropyrrolo[1,2-A]Pyrazine is a high-purity, heterocyclic organic building block of significant interest in advanced chemical synthesis. This compound matters as a versatile and critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and pesticides with enhanced efficacy.
• Material Science Research: Serves as a precursor for developing organic electronic materials, such as semiconductors and light-emitting diodes (OLEDs).
• Chemical Biology: Employed as a molecular probe or a building block for bioconjugation in proteomics and diagnostic assay development.
• Academic & Contract Research: Essential for methodological studies in organic chemistry and for custom synthesis projects in CROs (Contract Research Organizations).
• Scale-up Process Development: Used in optimizing synthetic routes from laboratory scale to pilot plant and commercial production.

Basic Information

Item	Details
Product Name	8-Bromo-4-Chloropyrrolo[1,2-A]Pyrazine
CAS No.	1416439-60-5
Molecular Formula	C7H4BrClN2
Molecular Weight	231.48 g/mol
Synonyms	8-Bromo-4-chloro-pyrrolo[1,2-a]pyrazine; 8-Bromo-4-chloro-1H-pyrrolo[1,2-a]pyrazine; Pyrrolo[1,2-a]pyrazine, 8-bromo-4-chloro-; 1416439-60-5; 8-Br-4-Cl-pyrrolopyrazine; 4-Chloro-8-bromopyrrolo[1,2-a]pyrazine
EINECS	Contact for details

Quality Control

Our 8-Bromo-4-Chloropyrrolo[1,2-A]Pyrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your R&D and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.