Description

tert-Butyl 4-Formyl-4-(Iodomethyl)Piperidine-1-Carboxylate is a high-value, multi-functional piperidine derivative that serves as a critical building block in advanced organic synthesis. This compound is particularly significant for its dual reactive sites—the aldehyde and iodomethyl groups—which enable sophisticated molecular construction and functionalization. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of complex bioactive molecules and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology & Proteomics: Serves as a versatile linker or scaffold for developing chemical probes, activity-based probes (ABPs), and PROTACs (Proteolysis Targeting Chimeras).
• Material Science Research: Employed in the development of specialty polymers, ligands for catalysis, and advanced organic frameworks.
• Medicinal Chemistry: Facilitates structure-activity relationship (SAR) studies and the exploration of new chemical space for drug discovery programs.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	tert-Butyl 4-Formyl-4-(Iodomethyl)Piperidine-1-Carboxylate
CAS No.	1416372-40-1
Molecular Formula	C12H20INO3
Molecular Weight	353.20 g/mol
Synonyms	1-Boc-4-formyl-4-(iodomethyl)piperidine; 4-Formyl-4-(iodomethyl)piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-formyl-4-(iodomethyl)-1-piperidinecarboxylate; 1-(tert-Butoxycarbonyl)-4-formyl-4-(iodomethyl)piperidine; Boc-4-formyl-4-(iodomethyl)piperidine; 4-(Iodomethyl)-4-formyl-piperidine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Formyl-4-(Iodomethyl)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.