Description

4-Amino-1,2-Piperidinedicarboxylic Acid 1-(1,1-Dimethylethyl) 2-Methyl Ester is a high-purity, protected amino acid derivative serving as a critical chiral building block in advanced organic synthesis. Its value lies in providing a structurally defined scaffold for constructing complex molecules with precise stereochemistry. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, especially for central nervous system (CNS) and cardiovascular targets.
• Peptidomimetic Synthesis: Used to incorporate constrained, non-natural amino acid motifs into peptide analogs to enhance metabolic stability and bioavailability.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides with specific chiral activity.
• Asymmetric Catalysis Ligand Precursor: Can be utilized in the synthesis of chiral ligands for asymmetric hydrogenation and other catalytic transformations.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex organic molecules for clients.

Basic Information

Product Name	4-Amino-1,2-Piperidinedicarboxylic Acid 1-(1,1-Dimethylethyl) 2-Methyl Ester
CAS No.	1416371-86-2
Molecular Formula	C13H24N2O4
Molecular Weight	272.34 g/mol
Synonyms	1-(tert-Butyl) 2-methyl 4-amino-1,2-piperidinedicarboxylate; tert-Butyl methyl 4-amino-1,2-piperidinedicarboxylate; 4-Amino-1,2-piperidinedicarboxylic acid 1-tert-butyl 2-methyl ester; 1-Boc-2-Methyl 4-amino-1,2-piperidinedicarboxylate; N-Boc-4-Amino-piperidine-1,2-dicarboxylic acid dimethyl ester (common misnomer); 4-Aminopiperidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester; Protected 4-Aminopiperidine-2-carboxylic Acid Derivative
EINECS	Contact for details

Quality Control

Our 4-Amino-1,2-Piperidinedicarboxylic Acid 1-(1,1-Dimethylethyl) 2-Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.