Description

2-Chloro-3-(Chloromethyl)Pyrazine Hydrochloride is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound is valued for its dual reactive sites, enabling its use as a key intermediate in the development of complex molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the pyrazine core for bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold for constructing complex heterocyclic libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Material Science: Investigated as a monomer or functionalizing agent in the development of specialty polymers and advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and fine chemical producers for use in multi-step, custom synthesis projects under cGMP or ISO standards.

Basic Information

Product Name	2-Chloro-3-(Chloromethyl)Pyrazine Hydrochloride
CAS No.	1416354-33-0
Molecular Formula	C5H5Cl2N2•HCl
Molecular Weight	209.48 g/mol
Synonyms	2-Chloro-3-(chloromethyl)pyrazine HCl; 2-Chloro-3-(chloromethyl)pyrazine hydrochloride; 3-(Chloromethyl)-2-chloropyrazine hydrochloride; Pyrazine, 2-chloro-3-(chloromethyl)-, hydrochloride; 2-Chloro-3-chloromethylpyrazine hydrochloride; (2-Chloro-3-pyrazinyl)methyl chloride hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-3-(Chloromethyl)Pyrazine Hydrochloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for research and commercial synthesis. A detailed Certificate of Analysis (COA) confirming identity, purity (typically ≥95% by HPLC), and impurity profile is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.