Description

(2S,5R)-Ethyl 5-(Benzyloxyamino)Piperidine-2-Carboxylate is a high-purity chiral piperidine derivative, serving as a critical advanced intermediate in modern pharmaceutical synthesis. Its defined stereochemistry and functional groups make it an essential building block for constructing complex molecules with specific biological activity. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly in areas requiring precise stereochemical control.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, including potential central nervous system (CNS) drugs and enzyme inhibitors.
• Organic Synthesis Building Block: Used in multi-step synthetic routes to introduce the (2S,5R)-piperidine-2-carboxylate moiety into more complex molecular architectures.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization processes to explore new chemical entities.
• Asymmetric Synthesis: Utilized as a starting material or intermediate in catalytic asymmetric transformations due to its pre-defined stereocenters.
• Process Chemistry Development: Serves as a reference standard or intermediate in scaling up synthetic pathways from laboratory to pilot plant scale.

Basic Information

Product Name	(2S,5R)-Ethyl 5-(Benzyloxyamino)Piperidine-2-Carboxylate
CAS No.	1416134-47-8
Molecular Formula	C15H22N2O3
Molecular Weight	278.35 g/mol
Synonyms	Ethyl (2S,5R)-5-(benzyloxyamino)piperidine-2-carboxylate; (2S,5R)-Ethyl 5-[(benzyloxy)amino]piperidine-2-carboxylate; 5-(Benzyloxyamino)piperidine-2-carboxylic acid ethyl ester, (2S,5R)-; UNII-9G8A8U5R4I; 9G8A8U5R4I; SCHEMBL21806227; AKOS025147319; A1-03426
EINECS	Contact for details

Quality Control

Our (2S,5R)-Ethyl 5-(Benzyloxyamino)Piperidine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and compliance with your specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.