Description

tert-Butyl 4-(6-Chloropyrazin-2-yl)piperidine-1-carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a piperidine core protected by a Boc (tert-butoxycarbonyl) group and a chloropyrazine moiety. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, CROs (Contract Research Organizations), and fine chemical manufacturers targeting therapeutic areas such as oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of small molecule drug candidates, particularly kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its modifiable functional groups.
• API Synthesis: Employed in the multi-step synthesis of complex target molecules for preclinical and clinical trials.
• Chemical Biology Probes: Serves as a scaffold for creating tool compounds to study biological pathways and target validation.
• Custom Synthesis: A starting material for contract manufacturing and bespoke chemical synthesis services.

Basic Information

Product Name	tert-Butyl 4-(6-Chloropyrazin-2-yl)piperidine-1-carboxylate
CAS No.	1415812-58-6
Molecular Formula	C14H18ClN3O2
Molecular Weight	295.77 g/mol
Synonyms	1-Boc-4-(6-chloropyrazin-2-yl)piperidine; 1-(tert-Butoxycarbonyl)-4-(6-chloropyrazin-2-yl)piperidine; 4-(6-Chloro-2-pyrazinyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; tert-Butyl 4-(6-chloro-2-pyrazinyl)-1-piperidinecarboxylate; 1415812-58-6; 4-(6-Chloropyrazin-2-yl)piperidine-1-carboxylic acid tert-butyl ester; Boc-4-(6-chloropyrazin-2-yl)piperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(6-Chloropyrazin-2-yl)piperidine-1-carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.