Description

Hydroxy-Amino-(Peg2-T-Butyl Ester)2 CAS NO 1415800-34-8 is a specialized bifunctional polyethylene glycol (PEG) derivative featuring terminal amino and hydroxyl groups protected by tert-butyl ester moieties. This compound is engineered to serve as a versatile and high-purity building block for advanced bioconjugation and pharmaceutical linker synthesis. It is primarily required by research institutions and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for developing targeted drug delivery systems, peptide modifications, and functionalized polymers.

Application

• Pharmaceutical Linker Synthesis: A key intermediate for creating cleavable or stable linkers in antibody-drug conjugates (ADCs) and other targeted therapeutics.
• Peptide & Protein Modification: Used to introduce PEG chains (PEGylation) to enhance solubility, stability, and circulation half-life of bioactive peptides and proteins.
• Polymer & Dendrimer Chemistry: Serves as a functional monomer or cross-linking agent for synthesizing biocompatible and functionalized polymers, hydrogels, and dendrimers.
• Bioconjugation Reagent: Facilitates the covalent attachment of drugs, dyes, or other molecules to targeting ligands like antibodies or peptides.
• Surface Functionalization: Employed to modify nanoparticles, quantum dots, or diagnostic assay surfaces to improve biocompatibility and enable further coupling.
• Research & Development: A valuable tool in medicinal chemistry and chemical biology for exploring new drug delivery platforms and biomaterial designs.

Basic Information

Product Name	Hydroxy-Amino-(Peg2-T-Butyl Ester)2
CAS No.	1415800-34-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	2,2'-(Ethane-1,2-diylbis(oxy))bis(ethan-1-amine), N-(tert-butoxycarbonyl)-, di-tert-butyl ester derivative; Amino-PEG2-alcohol, Boc-protected, t-butyl ester; 1-Amino-3,6-dioxa-8-hydroxyoctane, N-Boc, t-butyl ester derivative; Bifunctional PEG linker, amino-hydroxy, t-Bu protected; Boc-NH-PEG2-CH2CH2-O-tBu; Polyethylene glycol derivative, amino and t-butyl ester terminated; 1415800-34-8
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and pharmaceutical-grade intermediates. Each batch is characterized using advanced analytical techniques such as HPLC, NMR, and mass spectrometry to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We adhere to a quality management system to support our commitment to reliable supply and product integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccated environment to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid or viscous liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.