Description

tert-Butyl 4-(2-Morpholino-2-Oxoethyl)Piperazine-1-Carboxylate is a high-value, protected piperazine derivative that serves as a critical building block in advanced organic synthesis. Its molecular architecture, featuring both a Boc-protected piperazine and a morpholino amide moiety, makes it an essential intermediate for constructing complex pharmacologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new drug candidates, particularly within medicinal chemistry programs targeting CNS disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), especially for neurological and psychiatric targets.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns to introduce and modulate the piperazine-morpholine pharmacophore.
• Custom Synthesis: Serves as a versatile starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.
• Chemical Biology Probes: Utilized in the synthesis of tool compounds and probes for studying biological pathways and target engagement.
• Library Synthesis: An important building block for creating diverse screening libraries in drug discovery platforms.

Basic Information

Product Name	tert-Butyl 4-(2-Morpholino-2-Oxoethyl)Piperazine-1-Carboxylate
CAS No.	1415564-79-2
Molecular Formula	C15H27N3O4
Molecular Weight	313.40 g/mol
Synonyms	1-Boc-4-(2-Morpholino-2-oxoethyl)piperazine; tert-Butyl 4-(2-oxo-2-morpholinoethyl)piperazine-1-carboxylate; 4-(2-Morpholino-2-oxoethyl)piperazine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(2-morpholin-4-yl-2-oxoethyl)piperazine; Piperazine, 4-(2-morpholino-2-oxoethyl)-, 1-(1,1-dimethylethyl) ester; BOC-4-(2-Morpholinoacetoyl)piperazine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(2-Morpholino-2-Oxoethyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.